General Cell Lines and Cell Cultures
XenoTech,LLC Pooled Hartley Albino guinea pig liver cytosol, male, 1.0 ML at 10 ME/ML (10 ME)
Pooled Hartley Albino guinea pig liver cytosol, male, 1.0 ML at 10 ME/ML (10 ME)
Eurofins Discoverx PathHunter PTGIR Total Internalization U2OS Cell Line, 2 vials. (93-0838C3)
The PathHunter PTGIR Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of PTGIR via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged PTGIR and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the PTGIR receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Medchemexpress LLC Inducible T-cell co-stimulator (ICOS), rat, HEK293 Fc-fusion | >95.0% | 10 UG
Recombinant rat Inducible T-cell co-stimulator (ICOS) extracellular domain expressed in HEK293 cells as a C-terminal human Fc fusion. Supplied lyophilized and purified (>95%) from PBS, pH 7.4. Designed for in vitro immunology research including T-cell activation, receptor-ligand interaction assays, and biochemical characterization. For research use only.
- HEK293-expressed recombinant rat ICOS extracellular domain.
- C-terminal human Fc fusion for improved stability and detection.
- Lyophilized formulation from PBS, pH 7.4.
- Purity greater than 95% by reducing SDS-PAGE.
- Available in microgram-scale quantities for assay development.
Eurofins Discoverx cAMP Hunter CHO-K1 ADRB2 Gs Cell Line, 2 vials. (95-0121C2)
The cAMP Hunter ADRB2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB2, a naturally Gs coupled GPCR. Upon activation of ADRB2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 PTHR2 Gs Cell Line, 2 vials. (95-0057C2)
The cAMP Hunter PTHR2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. parathyroid hormone, TIP 39) based activation of PTHR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PTHR2, a naturally Gs coupled GPCR. Upon activation of PTHR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Electron Microscopy Sciences Precision Light Guide GI-20-6 with Stay-Put Gooseneck, 20" OAL, 6 mm glass diameter
Designed for use with microscopes, boroscopes, and endoscopes. Flexible and versatile, the light guides are ideal for a host of scientific, quality control and electronic applications. All of our light guides are backed by a full one-year warranty. Applications in stereochemistry, high/low contrast, optical comparators, IC/Semicondoctor etching and printing, automatic test equipment, profile projectors, and quality control.
Features fiber bundles that have been designed to provide brilliant specimen cross lightning from above and below. Only the finest quality optical class used. End fitting are polished stainless steel.
OAL: 20"
Diameter: 6 mm glass
Medchemexpress LLC UT-155, Solid + Solvent, 10 mM * 1 mL in DMSO ready for reconstitution
UT-155 is a selective and potent androgen receptor (AR) antagonist, with a Ki of 267 nM for UT-155 binding to AR-LBD.
Eurofins Discoverx PathHunter HEK 293 F2RL1 (PAR2, GPR11) β-Arrestin Cell Line, 2 vials. (93-0235C1)
The PathHunter F2RL1 (PAR2,GPR11) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. proteases, SLIGRL) based activation of F2RL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged F2RL1 and EA-tagged β-Arrestin-2. Activation of F2RL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 SCTR β-Arrestin Cell Line, 2 vials. (93-0237C2)
The PathHunter SCTR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SCTR and EA-tagged β-Arrestin-2. Activation of SCTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 DRD1 Gs Cell Line, 2 vials. (95-0083C2)
The cAMP Hunter DRD1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD1, a naturally Gs coupled GPCR. Upon activation of DRD1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.